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Table 1 Baseline characteristics of the included randomized controlled trials about depressive symptoms

From: Effects of physical activity on depressive and anxiety symptoms of women in the menopausal transition and menopause: a comprehensive systematic review and meta-analysis of randomized controlled trials

Author, year

Study location

Menopausal stage

Age, y

Active treatment

Duration, wk

Time/Intensity

Control treatment

Measures

Sample size active

Mean ± SD

Sample size control

Mean ± SD

Abedi et al. 2015

Iran

Postmenopausal

50–75

Walking

12w

Low intensity

No intervention

Beck Depression Inventory (BDI)

49

13.7 ± 5

48

19.6 ± 4.79

Afonso et al. 2012

Brazil

Postmenopausal

42–58

Yoga

2/w, 16w

60 min

Wait-list

Beck Depression Inventory (BDI)

15

11.0 ± 1.9

15

14.8 ± 1.9

Aibar-Almazán et al. 2017

Spain

Postmenopausal

50–75

Pilates

2/w, 12 w

60 min

No intervention

Hospital anxiety and depression scale (HADS)

55

3.98 ± 2.93

52

6.81 ± 3.6

Bernard et al. 2105

France

Postmenopausal

40–63

Walking

2/w, 6w

40 min, 40–75% maximal heart rate, moderate intensity

Wait-list

Beck Depression Inventory (BDI)

61

7.74 ± 0.77

60

10.52 ± 0.78

Bowen et al. 2006

USA

Postmenopausal

50–65

Aerobic exercise

5/w, 52w

45 min, 60–75% of VO2 max, moderate intensity

Stretching

Brief Symptom Inventory (BSI)

86

94.31 ± 10.4

86

93.45 ± 8.03

Carcelén-Fraile et al. 2022

Spain

Postmenopausal

60–70

Qigong

2/w, 12w

60 min

No intervention

Hospital anxiety and depression scale (HADS)

57

7.70 ± 3.23

60

10.07 ± 3.16

Elavsky et al. 2007

USA

Menopausal

40–62

Walking

3/w, 16w

60 min, 60–75% of the heart rate reserve (HRR), moderate intensity

Wait-list

Beck Depression Inventory (BDI)

63

6.38 ± 4.94

39

8.11 ± 7.64

Gao et al. 2016

China

Perimenopausal

40–62

Square dance

5/w, 12w

60–90 min

No intervention

Self-rating depressive scale (SDS)

26

0.15 ± 0.08

24

0.02 ± 0.09

Hu et al. 2017

China

Postmenopausal

45–60

Walking

3/w, 16w

60 min, 60% heart rate reserve, moderate intensity

Wait-list

Beck Depression Inventory-21 (BDI)

40

2.25 ± 1.24

40

3.85 ± 2.14

Imayama et al. 2011

USA

Postmenopausal

40–75

Aerobic exercise

5/w, 52w

45 min, 70–85% of maximal heart rate, moderate-to-vigorous intensity

Wait-list

Brief Symptom Inventory-18 (BSI-18)

117

48.1 ± 9.8

87

48.4 ± 9.6

Kai et al. 2016

Japan

Menopausal transition or postmenopausal

45–55

Stretching

7/w, 3w

10 min

Wait-list

Self-rating depressive scale (SDS)

20

35.8 ± 9.3

20

41.6 ± 7.3

Li et al. 2022

China

Postmenopausal

> 40

Baduanjin

5/w, 16w

45 min

Er Xian Decoction

Self-rating depressive scale (SDS)

17

47.06 ± 1.81

15

47.07 ± 2.19

Luoto et al. 2012

Finland

Menopausal

45–65

Aerobic training

4/w, 12w

50 min, 64-80% of maximal heart rate, moderate intensity

No intervention

Menopause-specific quality of life score (WHQ)

74

0.12 ± 0.2

77

0.22 ± 0.21

Newton et al. 2014

USA

Menopausal transition or postmenopausal

> 60

Yoga

2/w, 12w

90 min

No intervention

Patient Health Questionnaire-8 (PHQ-8)

99

-0.8 ± 3.55

133

0.1 ± 3.53

Noh et al. 2020

Korea

Menopausal

 

SaBang-DolGi walking

3/w, 12w

60 min

Usual care

Korea Symptom-Checklist-90-Revision (SCL-95-R)

21

43.57 ± 7.02

19

45.84 ± 8.94

Sen et al. 2020

Turkey

Postmenopausal

50–65

Whole-body vibration

3/w, 24w

20–60 min

No intervention

Beck depression inventory (BDI)

15

9 ± 3.3

18

15.9 ± 6.5

Sternfeld et al. 2014

USA

Late perimenopausal or postmenopausal

40–65

Exercise training

3/w, 12w

40–60 min, 50–70% of

heart rate reserve, moderate intensity

No intervention

Patient Health Questionnaire-8 (PHQ-8)

78

-0.9 ± 3.38

135

0.1 ± 3.53

Takahashi et al. 2019

Japan

Postmenopausal

45–55

increased physical activities

8 w

>=3METs, moderate to vigorous

intensity

No intervention

Geriatric Depression

Scale (GDS)

19

2.9 ± 1.7

19

2.9 ± 2.6

Villaverde Gutiérrez et al. 2012

Spain

Postmenopausal

 

Exercise training

2–3/w, 12w

50–60 min, 50–85% maximum heart rate reserve, moderate intensity

No intervention

Geriatric Depression Scale (GDS)

27

12.11 ± 2.4

30

15.05 ± 2.6

Zhao et al. 2020

China

Menopausal

50–70

24 forms taichi

3/w, 48w

60 min, 55–65% maximum heart rate reserve, moderate intensity

No intervention

Kupperman Scale

36

0.8 ± 0.7

38

1.8 ± 0.9