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Table 1 Characteristics of the 6,899 participants by cognitive function

From: Late-life physical activity, midlife-to-late-life activity patterns, APOE ε4 genotype, and cognitive impairment among Chinese older adults: a population-based observational study

 

Overall

Cognitive impairment

Cognitively normal

P-value

N

6899

1871

5028

Basic Characteristics

    

Age (years)

68 (65, 73)

69 (65, 74)

68 (65, 72)

< 0.01

Sex (female, %)

3848 (55.78%)

1198 (64.03%)

2650 (52.70%)

< 0.01

Education (%)

   

< 0.01

 Illiterate

2307 (33.44%)

777 (41.53%)

1530 (30.43%)

 

 Primary

1519 (22.02%)

341 (18.23%)

1178 (23.43%)

 

 Junior and higher

3073 (44.54%)

753 (40.25%)

2320 (46.14%)

 

Occupation (%)

   

< 0.01

 Technical and managerial personnel

953 (13.81%)

129 (6.89%)

824 (16.39%)

 

 Service and sales personnel

1045 (15.15%)

215 (11.49%)

830 (16.51%)

 

 Manual worker

4887 (70.84%)

1524 (81.45%)

3363 (66.89%)

 

Body mass index (kg/m2)

24.40 (22.40, 26.60)

24.30 (22.30, 26.70)

24.40 (22.40, 26.50)

0.80

Waist-to-hip ratio

0.89 (0.85, 0.93)

0.89 (0.85, 0.93)

0.89 (0.85, 0.93)

0.32

Healthy dietary habits (yes, %)

495 (7.17%)

103 (5.51%)

392 (7.80%)

< 0.01

Smoking (%)

   

< 0.01

 Never

5149 (74.63%)

1483 (79.26%)

3666 (72.91%)

 

 Former

744 (10.78%)

160 (8.55%)

584 (11.61%)

 

 Current

1006 (14.58%)

228 (12.19%)

778 (15.47%)

 

Alcohol intake (%)

   

< 0.01

 Hardly ever drinks

4585 (66.46%)

1372 (73.33%)

3213 (63.90%)

 

 Less than weekly

1344 (19.48%)

273 (14.59%)

1071 (21.30%)

 

 Weekly

970 (14.06%)

226 (12.08%)

744 (14.80%)

 

Sedentary time (minutes/day)

240 (120, 330)

180 (120, 300)

240 (150, 360)

< 0.01

Functional limitations (yes, %)

293 (4.25%)

145 (7.75%)

148 (2.94%)

< 0.01

Diabetes (yes, %)

1079 (15.64%)

302 (16.14%)

777 (15.45%)

0.51

Hypertension (yes, %)

2579 (37.38%)

698 (37.31%)

1881 (37.41%)

0.96

APOE ε4 genotype*

   

0.01

 Non-carrier

5472 (79.32%)

1451 (77.55%)

4021 (79.97%)

 

 Carrier

1103 (15.99%)

333 (17.80%)

770 (15.31%)

 

Late-life physical activity levels

    

Total MET-minutes/week

3360 (1680, 5600)

3360 (1680, 5400)

3360 (1800, 5760)

< 0.01

Overall physical activity levels (category, %)

< 0.01

 Low level

429 (6.22%)

161 (8.61%)

268 (5.33%)

 

 Moderate level

526 (7.62%)

152 (8.12%)

374 (7.44%)

 

 High level

5944 (86.16%)

1558 (83.27%)

4386 (87.23%)

 

Work-related physical activity (yes, %)

5378 (77.95%)

1380 (73.76%)

3998 (79.51%)

< 0.01

Transport-related physical activity (yes, %)

6225 (90.23%)

1633 (87.28%)

4592 (91.33%)

< 0.01

Recreation-related physical activity (yes,%)

1535 (22.25%)

310 (16.57%)

1225 (24.36%)

< 0.01

Moderate-intensity physical activity (yes,%)

5506 (79.81%)

1403 (74.99%)

4103 (81.60%)

< 0.01

Vigorous-intensity physical activity (yes,%)

672 (9.74%)

149 (7.96%)

523 (10.40%)

< 0.01

Midlife-to-late-life activity patterns

    

Changes in physical activity levels from midlife to late life (%)

< 0.01

 Decreasing activity levels

5790 (83.93%)

1618 (86.48%)

4172 (82.98%)

 

 Maintaining activity levels

540 (7.83%)

106 (5.67%)

434 (8.63%)

 

 Increasing activity levels

569 (8.25%)

147 (7.86%)

422 (8.39%)

 
  1. *Only includes the 6,575 participants who have APOE genotyping data
  2. Continuous variables were described with median and interquartile range [IQR] due to abnormal distribution, and categorical variables with frequency and percentage. Differences between cognitive status groups were assessed using Wilcoxon rank-sum test for continuous variables, and Chi-square test for categorical variables