Fig. 1
Flow diagram of the inclusion of participants within the Energy for Life after ColoRectal cancer (EnCoRe) study from 2012 onwards and the number of post-treatment measurements available up to October 2021 included in the analyses of the current paper. 1Response rate = (persons with measurements)/(persons with measurements + persons lost to follow-up – persons died). The declining number of participants at subsequent time points is because not all participants included at diagnosis from April 2012 onwards had already reached all follow-up time points by July 2018 (6 weeks until 24 months post-treatment) or October 2021 (60 months post-treatment). 2Since the analyses in this paper were focused on diurnal rest-activity rhythms and fatigue, insomnia, and health-related quality of life (HRQoL) after colorectal cancer treatment, only post-treatment measurements with available data on diurnal rest-activity rhythms, fatigue, insomnia, or HRQoL, and covariates were included. 3Of the three persons without 6 weeks follow-up visits, one person did not have a 6 months follow-up visit before July 16th 2018. Of the six persons without 6 months follow-up visits, one person did not have a 12 months follow-up visit before July 16th 2018. 4All data collected from participants between April 2012 and July 2018 were used for the measurements from 6 weeks until 24 months post-treatment. In addition, these participants were followed over time and data was collected in October 2021 for the 60 months-treatment follow-up measurement