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Table 6 Difference in cost and effects (change in two or three behaviours and cardiovascular risk); ICER between intervention and control patients and Relative Value Index (RVI) for the main and sensitivity analyses based on adjusted models

From: Cost-effectiveness analysis of a multiple health behaviour change intervention in people aged between 45 and 75 years: a cluster randomized controlled trial in primary care (EIRA study)

 

Usual Care follow-up Cost (95% CI) in €

Usual care % Change in two or three in one patient (95% CI)

ICER (€/extra change in two or three behaviours in one patient)

RVI

Usual care REGICOR at follow-up (95% CI)

ICER (€/REGICOR reduction)

RVI

Main analysis - Societal perspective (ITT and minimum wage)

3,509.14 (2,097.21; 4,921.07)

8.95 (5.89; 12.01)

5598

0.07

5.32 (3.72; 6.92)

1,727

0.38

Main analysis – Healthcare system perspective (ITT and minimum wage)

2,342.46 (1,382.32; 3,302.62)

8.95 (5.89; 12.01)

3932

0.07

5.32 (3.72; 6.92)

1,231

0.36

Mean wage (Societal perspective)

3,823.72 (2,407.10; 5,240.34)

8.95 (5.89; 12.01)

8220

0.05

5.32 (3.72; 6.92)

2,536

0.28

Maximum regional tariffsa

4,382.76(2,717.33; 6,048.20)

8.95 (5.89; 12.01)

5051

0.10

5.32 (3.72; 6.92)

1,559

0.53

Minimum regional tariffs

2,840.45 (1,536.42; 4,144.47)

8.95 (5.89; 12.01)

6377

0.05

5.32 (3.72; 6.92)

1,590

0.34

Complete-case

3,396.87 (2,246.36; 4,547.365)

5.70 (4.38; 7.02)

2224

0.27

4.69 (4.37.; 5.00)

531

1.36

Unadjusted analysisb

3,509.14 (2,097.21; 4,921.07)

8.95 (5.89; 12.01)

7690

0.05

5.32 (3.72; 6.92)

2,226

0.30

SUR

3,509.14 (2,097.21; 4,921.07)

NA

NA

NA

5.32 (3.72; 6.92)

760

0.22

  1. All sensitivity analyses considered societal perspective. SUR: Seemingly unrelated regressions. a Minimum daily wage is maintained as unit cost for sick leave in this sensitivity analysis. b Only adjusted by baseline costs or effects. cConfidence interval in cost when CVR is consider as effect is (-1.58; 261.22). dConfidence interval calculated based on bootstrapping. NA: Not applicable due to the outcome not being a continuous variable